Biomedical Sensors and Subsystems

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Micro- and Nano-structured Dynamic Fluidic Systems
Ramsey Zeitoun, Thomas Westrich, and Mark A. Burns
(left) View of the whole device; (center) schematic of stream flow paths; (right) image of streams narrowing in device
(left) View of the whole device; (center) schematic of stream flow paths; (right) image of streams narrowing in device

Co-flowing laminar streams in microfluidic devices are used to create microsecond mixers, produce materials and guide light. These tools can benefit from the high-throughput, controlled nature of microfluidic systems by miniaturizing, scaling, and understanding co-flow. This has been addressed by designing a three-dimensional microfluidic device to actively miniaturize co-flowing streams to thicknesses of less than one micron. This architecture allowed for devices to scale both the size and number of co-flows. Up to 64 submicron streams were generated in a single microchannel. The quality of produced co-flows was investigated with respect to limitations of diffusion at low flow rates and Dean flow alterations at high flow rates.

Updated 06/13/2011